AstriVax – Strategic-Technological Analysis
AstriVax is a Belgian biotechnology venture pioneering a new approach to vaccines that could reshape Europe’s strategic health security. Founded in 2022 as a spin-off from KU Leuven’s renowned Rega Institute, the company has built a plug-and-play DNA vaccine platform designed to tackle some of the world’s most challenging viral diseases[1]. AstriVax’s core innovation enables the delivery of live-attenuated vaccines in a radically simpler way: using a thermostable DNA plasmid to launch a self-amplifying vaccine inside the patient[2]. This breakthrough means vaccines that traditionally required complex cold-chain logistics can now be produced and deployed with minimal temperature control – a game-changer for immunizations in remote or resource-limited settings[2]. Backed by one of the largest seed investments ever for a European university spin-off[3], AstriVax has rapidly attracted a team of top vaccine scientists and industry veterans. Its mission is more than business: it aligns with Europe’s quest for greater autonomy in critical health technologies, promising homegrown solutions to reduce reliance on foreign vaccine suppliers. With its first vaccines now in clinical trials[4], AstriVax stands at the intersection of biotech innovation and strategic resilience, offering a preview of how European ingenuity can bolster both public health and collective security.

